James P. Hardwick, Ph.D.
Associate Professor of Biochemistry/Molecular Pathology

Northeastern Ohio Universities
Colleges of Medicine and Pharmacy
4209 State Route 44, P.O. Box 95
Rootstown, Ohio 44272-0095
Phone: (330) 325-6684
E-Mail: jph@neoucom.edu

 

Education:

1981 Ph.D., Illinois State University, Normal, IL.
1978 M.S., Loyola University, Chicago, IL.
1973 B.A., Illinois College, Jacksonville, IL.

 

Professional Experience:

1990-Present Associate Professor, Department of Integrative Medical Sciences, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, Rootstown, OH.
1989-1991 Assistant Scientist, Adjunct Appointment Biomedical Research, Argonne National Laboratory, Argonne, IL.
1984-1989 Postdoctoral Fellow, Argonne National Laboratory, Argonne, IL.
1982-1984 Staff Fellow, National Institute of Environmental Health, Research Triangle Park, NC.
1981-1982 Postdoctoral Fellow, The McArdle Laboratory, University of Wisconsin, Madison, WI.

 

Recent Publications:

Dr. Hardwick's publications listed in PubMed

Osei-Hyiaman Douglas, Pal Pacher, B.J. Song, James P. Hardwick, and Ting-kai Li. Regulation of the CYP4F gene family in mice fed a high saturated fatty acid diet and in leptin receptor deficient mice. In preparation.

Bong-Jo Kim, Brian L. Hood, Richard A. Aragon, James P. Hardwick, Thomas P. Conrads, Timothy D. Veenstra, and Byoung J. Song. Increased oxidation and degradation of cytosolic proteins in alcohol-exposed mouse liver and hepatoma cells. Proteomics, 2006, 6:1250-1260.

Kwan-Hoon Moon, Brian L. Hood, Bong-Jo Kim, James P. Hardwick, Thomas P. Conrads, Timothy D. Veenstra, and Byoung J. Song. Inactivation of oxidized and S-nitrosylated mitochondrial proteins in alcoholic fatty liver of rats. Hepatology2006, 44:1218-1230.

Donelson, E., Zhang, X., Vernell R., and Hardwick, J.P. Genomic structure and regulation of the rat hepatic CYP4F1 gene by peroxisome proliferators. Achieves Biochem. Biophys.. Accepted 2007 minor revisions.

Hardwick, J.P., Peters J., Malmer M., and Gonzalez F.J. Regulation of the CYP4F1 leukotriene B4 omega hydroxylase gene during peroxisomal proliferator induced hepatocarcinogenesis in PPAR (+/+) and PPAR (-/-) knockout mice. Cancer Research, Submitted revisions.