Mary J. Cismowski, Ph.D.
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| 1990 | Ph.D., Department of Biochemistry, The Johns Hopkins University, Baltimore, MD. |
| 1983 | B.A., Magna cum laude, Biochemistry, Occidental College, Los Angeles, CA. |
Professional Experience:
| 2007-Present | Associate Professor, Department of Integrative Medical Sciences, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, Rootstown, OH. |
| 2003-2007 | Associate Professor Department of Physiology and Pharmacology, Northeastern Ohio Universities College of Medicine, Rootstown, OH. |
| 2002-2003 | Associate Scientist and Director, Laboratory for Cellular Signaling, The Guthrie Research Institute, Sayre, PA. |
| 2000-2002 | Senior Scientist, Molecular Biology, Neurocrine Biosciences, Inc., San Diego, CA. |
| 1990-2000 | Consultant, Proteome Incorporated, Beverly, MA. |
| 1997-1999 | Scientist II, Receptor Pharmacology/Biochemistry, Cadus Pharmaceutical Corporation, Tarrytown, NY. |
| 1999-2000 | Research Investigator, Pharmacology, OSI Pharmaceuticals, Tarrytown, NY. |
Recent Publications:
Dr. Cismowski's publications listed in PubMed
Lanier, S.M., Struckhoff, A., and Cismowski, M.J. (2007). Activator of G Protein Signaling 1. UCSD-Nature Molecule Pages (doi:10.1038/mp.a000226.01).
Cismowski, M.J. (2006) Non-receptor activators of heterotrimeric G-protein signaling (AGS proteins). Sem. Cell Dev. Biol 17:334-44.
Sato, M., Cismowski, M.J., Toyota, E., Smrcka, A.V., Lucchesi, P.A., Chilian, W.M., and Lanier, S.M. (2006) Identification of a receptor-independent activator of G-protein signaling (AGS8) in ischemic heart and its interaction with Gβγ. Proc. Natl. Acad. Sci. USA 103:797-802. (Selected as a "Must Read", Faculty of 1000 Biology: evaluations for Sato M. et al Proc Natl Acad Sci USA 2006 Jan 17 103(3):797-802.
Cismowski, M.J. and Lanier, S.M. (2005) Activation of heterotrimeric G-proteins independent of a G-protein coupled receptor and the implications for signal processing. Rev. Physiol. Biochem. Pharmacol. 155:57-80.
Blumer, J.G., Cismowski, M.J., Sato, M., and Lanier, S.M. (2005) AGS proteins diversity G-protein signaling. Trends Pharmacol. Sci. 26:470-476.
Cao, X., Cismowski, M.J., Wang, G., Vincent, T.S., Brown, K.D., and Lanier, S.M. (2004) Identification and characterization of AGS4: A GPR protein that regulates the activation state of Giα. J. Biol. Chem. 279:27567-27574.
Vaidyanathan, G., Cismowski, M.J., Wang, G., Vincent, T.S., Brown, K.D., and Lanier, S.M. (2004) The Ras-related protein AGS1/RASD1 suppresses cell growth.
Cepoi, D., Phillips, T., Cismowski, M.J., Goodfellow, V.S., Ling, N., Cone, R.D., and Fan, W. (2004) Assessment of a samll molecule melanocortin-4 receptor-specific agonist on energy homeostasis. Brain Res. 1000:64-71.
