Janis J. MacKichan, Pharm.D., FAPhA Chair Professor of Pharmacy Practice
Northeastern Ohio Universities College of Pharmacy 4209 St. Rt. 44, P.O. Box 95 Rootstown, Ohio 44272-0095 Phone: (330) 325-6475 Fax: (330) 325-5938 Email: jmackich@neoucom.edu

Janis J. MacKichan is professor and founding chair of the Department of Pharmacy Practice at Northeastern Ohio Universities College of Pharmacy. She received bachelor of science and doctor of pharmacy degrees from the University of Michigan, then completed a residency in hospital pharmacy at the University of Michigan and a clinical pharmacokinetics fellowship at the State University of New York at Buffalo. Dr. MacKichan was on the faculty of The Ohio State University College of Pharmacy for 13 years, where she taught and published in the areas of clinical pharmacokinetics and drug assay methods. Dr. MacKichan then served as the founding chair of the Department of Pharmacy Practice at Midwestern University Chicago College of Pharmacy for 14 years, where she focused on faculty recruitment and faculty development programs. During that time she received seven teaching awards as well as Midwestern University's highest honor, the Littlejohn Award, for dedication to service. The American Pharmacists Association (APhA) recently recognized Dr. MacKichan for "exemplary service and achievements" in her professional area by awarding her fellowship status in the APhA Academy of Pharmaceutical Research and Science.

Education:

Professional Experience:

Research Interests:

Clinical pharmacokinetics; serum protein binding of drugs; therapeutic drug monitoring; faculty development; learner-centered teaching.

Selected Publications:

JJ MacKichan and DH Doshi, "Pharmacokinetic Considerations for Drug Delivery," in Role of Drug Delivery Systems in Pharmaceutical Care: A Practitioner's Guide, M. Gibaldi, A Desai, M Lee, Eds. American Society of Health Systems Pharmacists. 2007; pp 11-22. (in press)

JJ MacKichan and S Andurkar, "Neurologic Disorders," in Role of Drug Delivery Systems in Pharmaceutical Care: A Practitioner's Guide, M. Gibaldi, A Desai, M Lee, Eds. American Society of Health Systems Pharmacists. 2007; pp 255-276. (in press)

JJ MacKichan, "Influence of Protein Binding and Use of Unbound (Free) Drug Concentrations," in Pharmacokinetics and Pharmacodynamic: Principles of Therapeutic Drug Monitoring, 4th Ed., WJ Evans, JJ Schentag and ME Burton, Eds., Applied Therapeutics, Inc., San Francisco, California. 2005; pp 82-120.

JJ MacKichan and M Lee, "Factors Contributing to Adverse Drug Events" in Drug-Induced Diseases: Prevention, Detection and Management, H. Manasee, Ed., American Society of Health Systems Pharmacists, 2005; pp 11-16.

JJ MacKichan, "Interpretation of Serum Drug Concentrations" in Basic Skills in Interpreting Laboratory Data, 3rd Ed., ML Lee, Ed., American Society of Health-System pharmacists, Bethesda Maryland. 2004; pp 117-182.

SW Leslie, GB Corcoran, JJ MacKichan, AS Undie, RP Vanderveen, KW Miller. Pharmacy scholarship reconsidered: The report of the 2003-2004 Research and Graduate Affairs Committee. Am J Pharm Educ.  2004; 68(3)S6.

JJ MacKichan and B J Shields, A one-month drug analysis laboratory rotation for Doctor of Pharmacy students, J Clin Pharmacol.  1993; 33(9): 790-796.

JJ MacKichan and WF Hink, High Performance liquid chromatographic determination of CGA-184699 (lufenuron) in cat and dog blood. J Liq Chromatogr. 1993; 16:2595-2604.

M Zakson, WF Hink and JJ MacKichan, Fate of the benzoylphenylurea, CGA-184699, in the cat flea, Ctenocephalides felis. Pesticide Science. 1992; 35:117-123

AK Rasymas, H Boudoulas and JJ MacKichan, Determination of verapamil enantiomers in serum following racemate administration using HPLC. J Liq Chromatogr. 1992; 15:3013-3029.

BJ Shields and JJ MacKichan, High performance liquid chromatographic method for the determination of metoclopromide in human plasma. J Liq Chromatogr. 1990; 13:2643-2659.

JJ MacKichan and T Bechtel, Quantitation of busulfan in plasma by high-performance liquid chromatography, J Chromatogr Biomed Appl. 1990; 532:424-428.

JJ MacKichan, Protein binding displacement interactions: Fact or Fiction? (Lead Article) Clin Pharmacokin. 1989; 16:65-73.

JJ MacKichan, H Boudoulas and SF Schaal, Effect of cimetidine on quinidine bioavailability and clearance. Biopharm Drug Dispos. 1989; 10:121-125.

DL Bremseth, JJ Lima and JJ MacKichan, Specific HPLC method for the separation of verapamil and four major metabolites after oral dosing. J Liq Chromatogr. 1988; 11:2713-2749.

JJ MacKichan, Specific high performance liquid chromatographic determination of quinidine in serum, blood and urine. Ther Drug Monit. 1987; 9:104-112.

JJ MacKichan and EM Zola, Determinants of carbamazepine and carbamazepine 10, 11-epoxide binding to serum protein, albumin and 1-acid glycoprotein. Brit J Clin Pharmacol. 1984; 18:487-493.

JJ MacKichan, R Schaal, R Stine and H Boudoulas, Indocyanine green clearance following single and chronic cimetidine doses. Res Commun Chem Pathol Pharmacol. 1984; 44:323-326.

JJ MacKichan, J Coyle, BJ Shields, H Boudoulas and JJ Lima, Fluoroimmunoassays for procainamide and N-acetylprocainamide compared with a liquid chromatographic method. Clin Chem. 1984; 30:768-773.

JJ MacKichan, Pharmacokinetic consequences of drug displacement from blood and tissue proteins. Clin Pharmacokin 9, Supplement 1: 32-41, 1984.