Core research interests in this field are:

Expression and distribution of extracellular matrix molecules such as collagen, and matrix receptors including integrins
(Kathleen Doane, Associate Professor, NEOUCOM)

Molecular Regulation of Cartilage Disease, Chondrocyte Endoplasmic Reticulum Stress, Tissue Engineering of Cartilage
(Walter E. Horton, Jr., Professor, NEOUCOM)

Interaction of mineral and organic matrix in vertebrate calcified tissues
(William J. Landis, Professor, NEOUCOM)

Effects of mechanical forces on mineralized tissues
(William J. Landis, Professor, NEOUCOM)

Recent Publications:

Kathleen J. Doane, Raka Bhattacharya, and Jeff Marchant 2002.
Perturbation of B1, Integrin Function Using Anti-Sense or Function-Blocking Antibodies on Corneal Cells Grown on Fibronectin and Tenascin. 
Cell Biology International, 26:131-144. 
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Scott J. Howell and Kathleen J. Doane 1998.
Type VI Collagen Increases Cell Survival and Prevents Anti-B1, Integrin-Mediated Apoptosis.
Experimental Cell Research, 241:230-241.
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W.E. Horton Jr., P. Bennion, L. Yang 2006.
Cellular, molecular, and matrix changes in cartilage during aging and osteoarthritis.
Journal of Musculoskeletal Neuronal Interactions 6 (4).
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Rieko Yagi, Denise McBurney, and Walter E. Horton, Jr., 2005.
Bcl-2 Positively Regulates Sox9-dependent Chondrocyte Gene Expression by Suppressing the MEK-ERK1/2 Signalig Pathway.
The Journal of Biological Chemistry, 280:30517-30525.
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Ling Yang, Sara G. Carlson, Denise McBurney, and Walter E. Horton, Jr., 2005.
Multiple Signals Induce Endoplasmic Reticulum Stress in Both Primary and Immortalized Chondrocytes Resulting in Loss of Differentiation, Impaired Cell Growth, and Apoptosis. 
The Journal of Biological Chemistry, 280:31156-31165.
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Philip L. Reno, Walter E. Horton Jr., Ruth M. Elsey, and C. Owen Lovejoy, 2007
Growth Plate Formation and Development in Alligator and Mouse Metapodials:  Evolutionary and Functional Implications.
Journal of Experimental Zoology (Mol Dev Evol) 308B:283-296
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Philip L. Reno, Denise L. McBurney, C. Owen Lovejoy, and Walter E. Horton Jr., 2006
Ossification of the Mouse Metatarsal:  Differentiation and Proliferation in the Presence/Absence of a Defined Growth Plate.
The Anatomical Record Part A 288A:104-118
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Kimberlee Potter, Donald E. Sweet, Paul Anderson, Graham R. Davis, Noritaka Isogai, Shinichi Asamura, Hirohisa Kusuhara, William J. Landis, 2006
Non-destructive studies of tissue-engineered phalanges by magnetic resonance microscopy and X-ray microtomography.
Bone, 38:350-358
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Robin Jacquet, Jennifer Hillyer, William J. Landis, 2005
Analysis of connective tissues by laser capture microdissection and reverse transcriptase-polymerase chain reaction.
Analytical Biochemistry, 337:22-34
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