Rats are routinely evaluated serologically for cilia-associated
respiratory bacillus (CARB), Mycoplasma pulmonis, pneumonia virus of
mice (PVM), Sendai virus, rat parvovirus (RPV), rat
coronavirus/sialodacryoadenitis virus (RCV/SDA), Kilham rat virus (KRV), and
H-1 virus. Once per year rats are also tested for Lymphocytic choriomeningitis virus and Reovirus. Pooled fecal samples from the sentinels in each housing room
are evaluated by fecal floatation exam and perianal tape tests from
individual animals are examined for evidence of intestinal parasites.
Additional testing is noted in "Comments". Breeding colonies are tested
quarterly and nonbreeding colonies are tested semiannually.
Interpretation of results follow the chart.
Caging Code:
C Conventional Shoe BoxH Hanging
SSM Sterile Static Microisolation
NSM Nonsterile Static Microisolation
SVM Sterile Ventilated Microisolation
NVM Nonsterile Ventilated Microisolation
Sp Special (see Comments).
Breeding: Y - Yes; N - No.
RAT HEALTH MONITORING RESULTS
|
Date |
Room No. |
Caging |
Breeding |
Results |
Comments | |
May/08 |
V-150 C |
C |
N |
All evaluations were negative for evidence of pathogens. |
A different diagnostic laboratory was used for the serological evaluations. The comprehensive testing performed once yearly was conducted. In addition to performing the standard tests listed in the summary description above, rats were also tested for Hantaan virus, Mouse adenovirus-1, Parvo NS-1, Rat Minute Virus, Theiler's murine encephalomyelitis virus-GDVII, Clostridium piliforme (etiology of Tyzzer's disease).
| |
V-150 F |
C |
N |
All evaluations were negative for evidence of pathogens.
|
A different diagnostic laboratory was used for the serological
evaluations. The comprehensive testing performed once yearly was
conducted. In addition to performing the standard tests listed in the
summary description above, rats were also tested for Hantaan virus, Mouse adenovirus-1, Parvo NS-1, Rat Minute Virus, Theiler's murine
encephalomyelitis virus-GDVII, Clostridium piliforme (etiology of
Tyzzer's disease). | |
V-171 |
C |
N |
All evaluations were negative for evidence of pathogens.
|
A different diagnostic laboratory was used for the serological
evaluations. The comprehensive testing performed once yearly was
conducted. In addition to performing the standard tests listed in the
summary description above, rats were also tested for Hantaan virus, Mouse adenovirus-1, Parvo NS-1, Rat Minute Virus, Theiler's murine
encephalomyelitis virus-GDVII, Clostridium piliforme (etiology of
Tyzzer's disease). | |
Date |
Room No. |
Caging |
Breeding |
Results |
Comments | |
Feb/08 |
|
|
|
|
No
testing performed on rats. Only breeding colonies of animals were
tested during this quarter, and no breeding rats were maintained during
this quarter.
| |
Date |
Room No. |
Caging |
Breeding |
Results |
Comments | |
Nov/07 |
V-150 C
|
C |
N |
All evaluations were negative for evidence of pathogens. |
| |
V-150 F |
C |
N |
All evaluations were negative for evidence of pathogens. |
| |
V-171 |
C |
N |
All evaluations were negative for evidence of pathogens.
|
| |
Date |
Room No. |
Caging |
Breeding |
Results |
Comments | |
Aug/07
|
|
|
|
|
No
testing performed on rats. Only breeding colonies of animals were
tested during this quarter, and no breeding rats were maintained during
this quarter. | |
Date |
Room No. |
Caging |
Breeding |
Results |
Comments | |
May/07 |
V-150 C |
C |
N |
All evaluations were negative for evidence of pathogens. |
Rats were also tested for Lymphocytic Choriomeningitis Virus and Reovirus. | |
V-150 F
|
C |
N |
All evaluations were negative for evidence of pathogens.
|
Rats were also tested for Lymphocytic Choriomeningitis Virus and Reovirus.
| |
Date |
Room No. |
Caging |
Breeding |
Results |
Comments | |
Feb/07
|
|
|
|
|
No
testing performed on rats. Only breeding colonies of animals were
tested during this quarter and no breeding rats were maintained during
this quarter. | |
Date |
Room No. |
Caging |
Breeding |
Results |
Comments | |
Nov/06 |
V-150 C |
C |
N |
Negative for all tests. |
| |
V-150 F
|
C | N |
Negative for all tests.
|
| |
Date |
Room No. |
Caging |
Breeding |
Results |
Comments | |
Aug/06 |
|
|
|
|
No
testing performed on rats. Only breeding colonies of animals were
tested during this quarter and no breeding rats were maintained during
this quarter.
| |
Date |
Room No. |
Caging |
Breeding |
Results |
Comments | |
May/06 |
V-150 C |
C |
N |
Negative for all tests. |
| |
V-150 F
|
C |
N |
Negative for all tests.
|
| |
Date |
Room No. |
Caging |
Breeding |
Results |
Comments | |
Feb/06
|
|
|
|
|
No
testing performed on rats. Only breeding colonies of rats were
tested at this time and none were maintained during this quarter. | |
Date |
Room No. |
Caging |
Breeding |
Results |
Comments | |
Nov/05
|
V-150 C |
C |
N |
Negative for all tests. |
| |
V-150 F |
C |
N |
Negative for all tests. |
| |
Date |
Room No. |
Caging |
Breeding |
Results |
Comments | |
Aug/05 |
|
|
|
|
No
testing performed on rats. Only breeding colonies of rats were
tested at this time and none were maintained during this quarter. | |
Date |
Room No. |
Caging |
Breeding |
Results |
Comments | |
May/05 |
V-150 A/G |
C |
N |
Negative for all tests. | | |
V-150 C |
C |
N |
Negative for all tests. | | |
V-150 F |
C |
N |
Negative for all tests. | | |
Discussion of Findings:
Effective
this quarter, the CMU is conducting a more complete serologic panel
(Rat Level II Profile as offered by BioReliance) on rats once yearly.
This quarter rats were tested serologically for CAR Bacillus,
Mycoplasma pulmonis, Pneumonia Virus of Mice, Rat Corona
virus/Sialodacryoadenitis virus, Reovirus, Sendai virus, H-1 virus,
Kilham Rat virus, Lymphocytic Choriomeningitis virus, and Parvovirus. |
|
Date |
Room No. |
Caging |
Breeding |
Results |
Comments | |
Feb/05 | | | | |
No testing was performed on rats. | |
Discussion of Findings:
Nothing to report. | |
Date |
Room No. |
Caging |
Breeding |
Results |
Comments | |
Nov/04 |
V-150 C |
C |
N |
Negative for all tests. | | |
V-150 F |
C |
N |
Negative for all tests. | | |
V-150 G |
C |
N |
Negative for all tests. | | |
Discussion
of Findings:
Nothing to report. | |
Date |
Room No. |
Caging |
Breeding |
Results |
Comments | |
Aug/04 | | | | |
No testing was performed on rats. | |
Discussion
of Findings:
Nothing to report. | |
Date |
Room No. |
Caging |
Breeding |
Results |
Comments | |
May-June/04 |
V-150 C |
C |
N |
Negative for all tests. | | |
V-150 F |
C |
N |
Negative for all tests. | | |
V-180 D |
SSM/C |
Y |
Negative for Hantaan virus. |
Animal were only tested for Hantaan virus. | |
Discussion
of Findings:
Serologic testing for Hantaan Virus was performed on 15 individual rats in preparation for shipment
to
Australia. All
tests were negative. | |
Date |
Room No. |
Caging |
Breeding |
Results |
Comments | |
Feb/04 |
V-180 D |
SSM/C |
Y |
Negative for all tests. | | |
Discussion
of Findings:
Nothing to report. | |
Date |
Room No. |
Caging |
Breeding |
Results |
Comments | |
Oct-Dec/03 |
V-150 B |
C |
N |
Negative for all tests. | | |
V-150 C |
C |
N |
Negative for all tests. | | |
V-150 F |
C |
N |
Negative for all tests. | | |
Discussion
of Findings:
Nothing to report. | |
Date |
Room No. |
Caging |
Breeding |
Results |
Comments | |
|